Drug-coated balloons versus bare metal stent for treatment of femoropopliteal lesions:36 month follow-up results of single center
10.3760/cma.j.cn112139-20210902-00415
- VernacularTitle:基于倾向性评分匹配的药物涂层球囊和金属裸支架治疗下肢动脉硬化效果的比较
- Author:
Jie FANG
1
;
Chengjia QU
;
Yongbao ZHANG
;
Lequn TENG
;
Jialiang LI
;
Chenyang SHEN
Author Information
1. 北京协和医学院 中国医学科学院 国家心血管病中心 阜外医院血管外科中心 100037
- Keywords:
Arteriosclerosis obliterans;
Treatment outcome;
Femoralartery;
Popliteal artery;
Drug-coated balloon;
Bare metal stent
- From:
Chinese Journal of Surgery
2021;59(12):975-979
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the therapeutic effects of drug-coated balloon (DCB) and bare metal stent (BMS) on primary femoropopliteal disease (FPAD) in the real world.Methods:This was a retrospective analysis of single-center follow-up results at 12,24,and 36 months of patients with FPAD lesions that were treated with DCB and BMS at Department of Aortic and Vascular Surgery, Fu Wai Hospital.One-to-one propensity score matching(PSM) was performed to balance the covariance between DCB group (137 cases) and BMS group (100 cases). Freedom from clinically driven target lesion reintervention rate(fCD-TLR) was determined by Kaplan-Meier curve.Log-rank test was used to compare the rates of fCD-TLR between DCB and BMS groups at 12,24,36 months post-operation.Results:After PSM, there were both 71 patients in each group,aged (68.0±9.6) years(range: 46 to 90 years) and (68.8±7.3) years(range: 48 to 87 years),lesion lengths were (119.6±14.2)mm(range:40 to 380 mm) and (110.8±13.1)mm(range:40 to 400 mm). The median follow-up period were 24.3 months (range:5.8 to 55.1 months).There was no death,amputation or reintervention within the 30 days after operation.The rates of fCD-TLR for DCB group at 12,24 and 36 months were 97.2%,85.9%,69.1%, and 95.8%,83.1%,59.2% for BMS group.There was no statistical difference between the two groups by Log-rank test ( P=0.551). Conclusion:DCB and BMS can both maintain favorable clinical effects in FPAD patients at 12,24,36 months post-operation.
