Diagnosis and surgical management of craniofacial deformities in acromegaly
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn114453-20231023-00107
   		
        
        	
        		- VernacularTitle:肢端肥大症颅颌面畸形的诊治
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xinyan CHEN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiaolei JIN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 中国医学科学院北京协和医学院整形外科医院颅颌面外科,北京 100144
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Acromegaly;
			        		
			        		
			        		
				        		Craniofacial deformity;
			        		
			        		
			        		
				        		Face recognition
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Plastic Surgery
	            		
	            		 2024;40(9):1012-1017
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Acromegaly is a chronic disease predominantly caused by the hypersecretion of growth hormone (GH), typically due to a pituitary adenoma. The characteristic craniofacial deformities include pronounced zygomatic arches, frontal bossing, prognathism, dental malocclusion and macroglossia. It’s recommended that facial reconstructive interventions be deferred until the patient’s serum GH levels have been consistently normalized for at least 12 months. This review summarized the current knowledge on diagnosis, screening and facial management strategies for this disease.