Infection and antibiotic application strategies of prosthetic breast reconstruction
10.3760/cma.j.cn114453-20191224-00384
- VernacularTitle:假体乳房再造术的感染与抗生素应用策略
- Author:
Yaping QU
1
;
Jie LUAN
Author Information
1. 中国医学科学院北京协和医学院整形外科医院乳房整形与美容中心 100144
- Keywords:
Breast reconstruction;
Prosthesis;
Infection;
Antibiotics
- From:
Chinese Journal of Plastic Surgery
2020;36(10):1156-1159
- CountryChina
- Language:Chinese
-
Abstract:
Prosthetic breast reconstruction is the most common surgical procedure for breast reconstruction after breast cancer surgery, but the high rate of postoperative infection is a major cause of failure of reconstruction surgery. Currently there are strict restrictions on the use of perioperative antibiotics in surgery, making it more difficult for clinicians to control postoperative infections after prosthetic reconstruction. Until now, there is still a different understanding of whether antibiotics can be used locally in prosthetic breast reconstruction, and there is a lack of consensus on the method and timing of perioperative antibiotic use. This review systematically summarized current infections, factors, and strategies of prosthetic breast reconstruction. Taken together, the incidence of infection after prosthetic breast reconstruction (2.5% to 24.0%) is significantly higher than other clean procedures. The application of expander or prostheses, acellular allogeneic dermis, adjuvant radiotherapy and long-time drainage are factors that increase the rate of infection in prosthetic breast reconstruction. Prophylactic application of antibiotics and flushing the prosthesis with a mixed antibiotic solution into the cavity can effectively reduce the incidence of infection after breast reconstruction. The pros and cons of prolonging the use of antibiotics after surgery need further research. In case of infection after prophylactic application of antibiotics, alternative antibiotics are required.
