Relationship of operation manner and postoperative recurrence of hepatocellular carcinoma

VernacularTitle:手术方式与肝癌患者术后复发的关系
Author: Xiaofeng DONG ¹ ; Jingtao ZHONG ; Tianqi LIU ; Jianrong YANG
Author Information

1. 广西壮族自治区人民医院肝胆胰脾外科，南宁　530021
Keywords: Hepatocellular neoplasms; Operation; Recurrence
From: Chinese Journal of Oncology 2021;43(6):635-637
CountryChina
Language:Chinese
Abstract: Hepatocellular carcinoma (HCC) owns the high morbidity and mortality rates. Surgical resection is still the major pathway for the longer survival of HCC patients. Postoperative recurrence and metastasis have become the key impairment of prognosis of HCC patients. The relationship between tumor recurrence and surgical manner underwent by HCC patients is complicated and multiple factors are included. When the liver tumor was pressured during operation, tumor cells could be squeezed into blood flow via the broken vessels, which resulted in tumor metastasis. Besides, ischemia-reperfusion injury induced by Pringle maneuver during the liver blood blockade resulted in the immune destruction of liver and induced tumor recurrence.The destruction of physical barriers consisted of interstitial cells and normal liver cells was also a key factor for tumor recurrence. This paper summarizes the possible relationship between postoperative recurrence and surgical manner in HCC patients to provide the preventive suggestions for the postoperative recurrence of HCC patients.