Effect of nocturnal oxygen therapy combined with tiotropium bromide on pulmonary function and quality of life in elderly patients with COPD and respiratory failure
10.7619/jcmp.201709008
- VernacularTitle:夜间氧疗联合噻托溴铵对老年慢性阻塞性肺疾病合并呼吸衰竭患者肺功能及生活质量的影响
- Author:
Xinnian LIU
1
;
Caixia ZHANG
;
Fang LIU
;
Xiaoying ZHANG
Author Information
1. 湖北省第三人民医院 呼吸内科
- Keywords:
respiratory failure;
chronic obstructive pulmonary disease;
elderly;
nocturnal oxygen therapy;
tiotropium bromide;
quality of life
- From:
Journal of Clinical Medicine in Practice
2017;21(9):31-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of nocturnal oxygen therapy combined with tiotropium bromide on pulmonary function and quality of life in elderly patients with chronic obstructive pulmonary disease (COPD) and respiratory failure.Methods A total of 64 elderly patients with COPD and respiratory failure were selected.The 32 patients treated with conventional treatment and nocturnal oxygen therapies were designed as control group,and the otheR32 patients treated with nocturnal oxygen therapy and tiotropium bromide were designed as observation group.The clinical effect,pulmonary function and quality of life were compared between the two groups.Results AfteRtreatment,the p(O2),p(CO2),score of MMRC and 6-minute walking distance in the observation group were significantly betteRthan the control group (P<0.05).Improvement of pulmonary function and total healthy score in the observation group were significantly betteRthan the control group (P<0.05).Conclusion Nocturnal oxygen therapy combined with tiotropium bromide is effective in treatment of elderly patients with COPD and respiratory failure.
