Analysis of global coronavirus vaccine development situation
10.3760/cma.j.cn112866-20200402-00106
- VernacularTitle:全球冠状病毒疫苗研发态势分析
- Author:
Jun LIU
1
;
Fenghua LIU
;
Hailan WU
;
Zhenlong ZHANG
Author Information
1. 国药中生生物技术研究院有限公司信息办公室，北京 101111
- Keywords:
Coronavirus vaccine;
2019-nCoV;
Technical route;
Clinical trials;
Patent
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(4):357-366
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide references for accelerated development of novel coronavirus vaccines.Methods:Based on the Cortellis database, we analyzed and summarized the current research and development situation and technology layout of global coronavirus vaccines by searching the development status, technical route, clinical trials, and patents of global coronavirus vaccines in this article.Results:There are eighty-seven kinds of coronavirus vaccines under development in the world, mainly for 8 indications; among them, recombinant viral vector vaccines, protein subunit vaccines, and nucleic acid vaccines are widely used. There are 38 clinical trials, and most of them are at early-phase. The types of patents are mainly macromolecule product, biotechnological therapy, formulation, drug discovery and screening, and process.Conclusions:This comprehensive analysis of the development situation and technical layout of coronavirus vaccines will provide references and assistance for the development of new coronavirus vaccines.
