Research progress in BK virus infection after renal transplantation

VernacularTitle:肾移植术后BK病毒感染的研究进展
Author: Chun LIU ¹ ; Daihong LI
Author Information

1. 天津市第一中心医院，天津　300192
Keywords: BK virus; Renal transplantation; Renal allograft dysfunction; BK virus-associated nephropathy
From: Chinese Journal of Experimental and Clinical Virology 2020;34(3):333-336
CountryChina
Language:Chinese
Abstract: BK virus (BKV) belongs to a subtype of human polyomavirus, which was first reported in 1971. It is not pathogenic and lurks in urinary epithelial cells for a long time after infection in normal people. In recent years, BKV has been found to be reactivated and replicated in patients after renal transplantation, resulting viruria and viremia, which in turn leads to BKV-associated nephropathy (BKVAN) and finally cause renal allograft dysfunction. Therefore, the research on BKV and its associated nephropathy is becoming more and more in-depth. This review describes the epidemiology, laboratory diagnosis and treatment of BKV.