Analysis methods and case analysis of effect modification (2): effect modification in network Meta-analysis
10.3760/cma.j.cn112338-20230824-00094
- VernacularTitle:效应修饰作用分析方法与案例解析系列（二）：网状Meta分析中的效应修饰
- Author:
Fengqi LIU
1
;
Zhirong YANG
;
Shanshan WU
;
Houyu ZHAO
;
Siyan ZHAN
;
Feng SUN
Author Information
1. 北京大学公共卫生学院流行病与卫生统计学系，北京 100191
- Keywords:
Network Meta-analysis;
Effect modification;
Subgroup analysis;
Network Meta-regression
- From:
Chinese Journal of Epidemiology
2024;45(2):273-278
- CountryChina
- Language:Chinese
-
Abstract:
This paper briefly introduces the characteristics, research significance, and global reporting status of effect modification in network Meta-analysis, demonstrates the heterogeneity caused by effect modification in network Meta-analysis, and emphasizes the importance of exploring effect modification in network Meta-analysis. This paper also summarizes the normalized description and analysis strategies of effect modification in network Meta-analysis. Finally, by the case of "comparison of efficacy of three new hypoglycemic drugs in reducing body weight in type 2 diabetes patients", this paper demonstrates the realization of subgroup analysis and network Meta-regression in exploring effect modification, summarizes the advantages and disadvantages of the two methods, to provide references for future researchers.
