A sero-epidemiological survey of hepatitis B virus among the population over 18 year old in Chaoyang District of Beijing, 2020
10.3760/cma.j.cn112338-20220728-00670
- VernacularTitle:2020年北京市朝阳区18岁及以上人群乙型肝炎血清流行病学调查
- Author:
Qian QIU
1
;
Yan LIANG
;
Qian LI
;
Xiuying LIU
;
Wei ZHANG
;
Zheng ZHANG
;
Wei ZHAO
;
Li NIE
;
Xinghuo PANG
Author Information
1. 北京市疾病预防控制中心科研与教学管理办公室，北京 100013
- Keywords:
Hepatitis B virus;
Sero-epidemiological survey;
Hepatitis B surface antigen;
Hepatitis B surface antibody;
Hepatitis B core antibody
- From:
Chinese Journal of Epidemiology
2023;44(2):263-267
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the infection status of the hepatitis B virus among the population over 18 years old in the Chaoyang District of Beijing from August to December 2020.Methods:A multistage stratified cluster random sampling was carried out on residents over 18 years old who lived in Chaoyang for more than six months in 2020. The estimated sample size was 8 525. A blood sample was collected and tested for HBsAg, anti-HBs, and anti-HBc using the Abbott Microparticle Enzyme Immunoassay method. A questionnaire survey was also conducted.Results:A total of 9 875 residents were included; the overall positive rate of HBsAg, anti-HBc, and anti-HBs was 2.8% (95% CI:2.5%-3.1%), 33.9% (95% CI:33.0%-34.9%) and 45.6% (95% CI:44.6%-46.6%), respectively. The negative rate for all three serological markers was 45.9% (95% CI:44.9%-46.9%). The reported hepatitis B vaccination rate was 22.4%. The positive rate of HBsAg and anti-HBc were lower in group aged 18-28 years (1.9% and 6.8%, respectively) than the others, and that of the male was higher (3.6% and 35.4%, respectively) than the female (2.2% and 32.8%, respectively). The negative rate for all three serological markers increased with age. However, the positive rate of anti-HBs decreased with age. Conclusions:In Chaoyang District of Bejing, HBV prevalence among the population over 18 years old has decreased. The publicity and education about hepatitis B prevention and control should be strengthened to reduce the immunization gap of the population further.
