Epidemiological characteristics of a case infected with avian influenza A (H5N6) virus associated with exposure to aerosol
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.0254-6450.2020.03.015
   		
        
        	
        		- VernacularTitle:一起气溶胶暴露引起人感染H5N6禽流感病毒的流行病学调查
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yanhui LIU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jianyun LU
			        		
			        		;
		        		
		        		
		        		
			        		Wenhui LIU
			        		
			        		;
		        		
		        		
		        		
			        		Yu MA
			        		
			        		;
		        		
		        		
		        		
			        		Lan CAO
			        		
			        		;
		        		
		        		
		        		
			        		Kuibiao LI
			        		
			        		;
		        		
		        		
		        		
			        		Tiegang LI
			        		
			        		;
		        		
		        		
		        		
			        		Zhoubin ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Zhicong YANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 广州市疾病预防控制中心 510440
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Influenza A (H5N6);
			        		
			        		
			        		
				        		Aerosol;
			        		
			        		
			        		
				        		Epidemiological investigation
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Epidemiology
	            		
	            		 2020;41(3):358-362
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To investigate the epidemiological and clinical characteristics of a case infected with avian influenza A (H5N6) virus associated with exposure to aerosol and provide evidence for the prevention and control of human infection with avian influenza virus.Methods:Epidemiological investigation was conducted to identify the history of exposure, infection route, and disease progression. Real-time fluorescent quantitative RT-PCR was used to test the samples collected from the case, close contacts, environment and poultry market.Results:The case had no history of exposure to live poultry and poultry market. But before the onset the case had a history of exposure to the live poultry placed in a car with doors and windows closed. The samples collected from the case’s lower respiratory tract and the remaining frozen chicken meat were all influenza A (H5N6) virus positive.Conclusions:The source of infection was the live poultry, and the infection route might be the exposure to aerosol in a car with doors and windows closed, where the poultry were temporarily stored. It is necessary to promote centralized poultry slaughtering, cold chain distribution and fresh poultry sale, as well as strengthen health education and establish the concept of consuming fresh poultry.