Immune responses of pulpodentinal complex during caries progression
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn112144-20231204-00278
   		
        
        	
        		- VernacularTitle:龋病进展过程中牙髓牙本质复合体的免疫反应
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Ru ZHANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Benxiang HOU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 首都医科大学口腔医学院牙体牙髓科,北京 100050
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Dental caries;
			        		
			        		
			        		
				        		Dental pulp;
			        		
			        		
			        		
				        		Dentin;
			        		
			        		
			        		
				        		Caries prevention and treatment;
			        		
			        		
			        		
				        		Pulpodentinal complex;
			        		
			        		
			        		
				        		Immune response
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Stomatology
	            		
	            		 2024;59(9):966-970
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Caries is an infectious disease in which the invasion of pathogens and their metabolites can activate the recognition and defense system of the pulpodentinal complex. In-depth understanding of the immune responses mediated by the pulpodentinal complex will help to estimate the real state of the dental pulp during the progression of caries and to take reasonable clinical treatment strategies, which can be more targeted and less invasive. Based on the physiology of the pulpodentinal complex, the present article introduce its immunocompetence and mechanism, reactive changes, clinical intervention and its significance during the caries progression, as to improve diagnostics as well as treatment strategies for caries.