Research progress in functional regeneration methods and mechanisms of taste buds
10.3760/cma.j.cn112144-20231012-00190
- VernacularTitle:舌上皮味蕾功能性再生方法及机制的研究进展
- Author:
Jiran WANG
1
;
Ruiqi LI
;
Xiaofeng HUANG
Author Information
1. 首都医科大学附属北京友谊医院口腔科，北京 100050
- Keywords:
Regeneration;
Taste;
Taste buds;
Hedgehog proteins
- From:
Chinese Journal of Stomatology
2024;59(4):389-393
- CountryChina
- Language:Chinese
-
Abstract:
Gustation is one of the most important human senses. Taste dysfunctions, which may be due to aging, tongue cancer surgery, radiotherapy and chemotherapy, affect life quality. That is why the need for taste bud regeneration has received more attention. At present, research on development and renewal of taste cells provides a basis for taste bud regeneration; molecular mechanisms related to taste bud regeneration are being continuously uncoverd, aiding in the identification of more accurate targets for therapy. New methods such as nerve regeneration, tissue engineering, and cytokine therapy have emerged. The author reviews the mechanism and the latest methods of taste bud regeneration of lingual epithelium, aiming to open new horizions for the prevention and treatment of gustatory diseases, and provide theoretical references for its regeneration.
