Research status of non-coding RNA in viral myocarditis

VernacularTitle:非编码RNA在病毒性心肌炎中的研究现状
Author: Xiao-Long HE ¹ ; Xin-Xin HU ; Fan-Ning WANG ; Wen-Xin WANG ; Guo-Lei ZHOU ; Kang YI ; Tao YOU
Author Information

1. 甘肃中医药大学第一临床医学院,甘肃兰州 730000;先天性心脏病诊疗甘肃省国际科技合作基地,甘肃兰州 730000
Keywords: non-coding RNA; viral myocarditis; Coxsackievirus
From: The Chinese Journal of Clinical Pharmacology 2024;40(14):2143-2147
CountryChina
Language:Chinese
Abstract: Viral myocarditis(VMC)is the leading cause of dilated cardiomyopathy,which can lead to heart failure and sudden cardiac death.With the development of high-throughput sequencing technology,non-coding RNA(ncRNA)plays an important role in the occurrence and development of VMC.ncRNA promotes the occurrence and development of VMC by regulating viral replication,immune cell function,myocardial cell death,myocardial interstitial fibrosis,and other pathological processes.This article reviews the research progress of ncRNA in VMC and provides new ideas for the pathogenesis,diagnosis,and treatment of VMC.