Research progress on verteporfin in tumor treatment
10.13699/j.cnki.1001-6821.2024.12.031
- VernacularTitle:维替泊芬在肿瘤治疗中的作用研究现状
- Author:
Jia-Yi LI
1
;
Xi-Ming XU
Author Information
1. 武汉大学 人民医院肿瘤中心,湖北 武汉 430060
- Keywords:
verteporfin;
tumor;
photodynamic therapy;
programmed cell death 1 ligand 1
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(12):1844-1848
- CountryChina
- Language:Chinese
-
Abstract:
To treat age-related macular degeneration(AMD),verteporfin has been widely used for more than 20 years in ophthalmology as a photodynamic agent.In recent years,researchers have found that,in addition to the therapeutic effect of verteporfin on age-related macular degeneration,it also has great potential in the treatment of tumors.The killing effect of verteporfin on tumors has been studied and reported in a large number of studies.It can not only kill tumor cells under visible light as a photodynamic agent,but also kill tumor cells directly under non-photoactivated conditions.This article mainly reviews the current research status of verteporfin's role in cancer treatment.
