Case analysis of glucocorticoid therapy for recurrent fever after coronavirus disease 2019 infection in eldly patients
10.13699/j.cnki.1001-6821.2024.01.025
- VernacularTitle:糖皮质激素治疗老年新型冠状病毒感染后反复发热的病例分析
- Author:
Mei-Yu DENG
1
;
Xu-Hong YU
;
Ling-Hui ZHANG
;
Ling CHEN
Author Information
1. 中国人民解放军第三○五医院呼吸内科,北京 100017
- Keywords:
glucocorticoid therapy;
coronavirus disease 2019 infection;
recurrent fever;
eldly patient
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(1):121-125
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics and therapeutic method in the eldly patients with recurrent fever after coronavirus disease 2019(COVID-19)infection.Methods The data of 4 eldly patients with recurrent fever after COVID-19 infection was collected and their clinical characteristics and efficacy of glucocorticoid therapy were analyzed.Results Three patients were male and 1 was female,their ages were 82-86 years old,fever time was 24-37 days.Lung lesions in 3 patients were mild and 1 was severe.Low dose glucocorticoid was used in 2 cases(the initial dose of methylprednisolone tablets was 20 mg daily).The higher initial dose was used in 2 other cases(methylprednisolone,40 mg daily).The duration of fever reduction was 2-4 days.The treatment course of glucocorticoid was as short as 3-6 weeks for the 3 patients with mild lung lesions,and as long as 23 weeks for the patient with severe lung lesion.Conclusion For eldly patients with recurrent fever after COVID-19 infection,if the lung lesion was mild,a small dose of glucocorticoid and a short course of treatment may be used;if the lung lesion was severe,the dose can be increased appropriately and the course of treatment prolonged.
