Current status of neuroprotective agents in the treatment of acute ischemic stroke
10.13699/j.cnki.1001-6821.2018.06.033
- VernacularTitle:神经保护药治疗急性缺血性脑卒中的研究现状
- Author:
Ya-Ming DU
1
;
Zhi-Gang ZHAO
Author Information
1. 首都医科大学附属北京天坛医院药学部
- Keywords:
neuroprotective;
acute ischemic stroke;
calcium channel antagonist;
excitatory amino acid receptor antagonist;
free radical scavenger
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(6):725-727
- CountryChina
- Language:Chinese
-
Abstract:
The treatment of acute ischemic stroke includes early thrombolysis and neuroprotective therapy.Early thrombolysis is limited by time window,with only a few beneficiaries.Neuroprotective therapy blocks the death of nerve cells by blocking ischemic cascade.In this paper,the research progress of neuroprotective drugs in the treatment of acute ischemic stroke was summarized and the rationality of their use in clinic was discussed.