Progress in search for mechanism of Tanshinone Ⅱ A's against colon cancer
10.13699/j.cnki.1001-6821.2018.05.030
- VernacularTitle:丹参酮ⅡA抗结肠癌作用机制研究进展
- Author:
Xiu-Yue WANG
1
;
Chuan ZHAO
;
Wen-Jing LI
;
Che CHEN
;
Yong WANG
;
Hui-Yuan CHU
;
Yong-Juan LIANG
;
Jing-Ying LI
Author Information
1. 甘肃中医药大学 临床医学院
- Keywords:
traditional Chinese medicine;
Tanshinone Ⅱ A;
colon cancer;
cardiovascular disease
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(5):597-599
- CountryChina
- Language:Chinese
-
Abstract:
Tanshinone Ⅱ A (Tan Ⅱ A) is an extract of traditional Chinese medicine Salvia miltiorrhiza,which can play a natural antioxidant effect.It is mainly used in the treatment of cardiovascular disease.Which has anti-atherosclerosis,reduced myocardial infarct size and improve myocardial oxygen consumption,inhibition of thrombosis,inhibition of platelet aggregation,antitumor activity and other effects,and are mainly used for the treatment of cardiovascular disease in clinical applications.In recent years,a large number of clinical studies and animal experiments have confirmed that tanshinone Ⅱ A in the inhibition of colon cancer cell proliferation,promote cell apoptosis,promote cell invasion and metastasis and other aspects of prominent anti-cancer effect,making it the object of concern to researchers.In this paper,tanshinone ⅡA anti-colon cancer effect of studies were reviewed.
