Clinical analysis of dexmedetomidine in intraoperative wake -up test during language functional surgery with narcotrend monitor
10.13699/j.cnki.1001-6821.2015.19.008
- VernacularTitle:Narcotrend监测下右美托咪啶在语言功能区手术中唤醒麻醉的临床研究
- Author:
Bao-Lin ZHONG
1
;
Gui-Ming HUANG
;
Yi-Ping LI
;
Yi-Jian CHEN
;
You-Chun LI
Author Information
1. 赣州市人民医院 麻醉科
- Keywords:
Narcotrend;
dexmedetomidine;
language functional surgery;
wake-up test;
anesthesia
- From:
The Chinese Journal of Clinical Pharmacology
2015;31(19):1916-1918
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of dexmedetomidine in intraoperative wake -up test during language functional surgery with nar-cotrend monitor.Methods Forty patients needing language functional surgery were randomly divided into treatment group and control group , which were pumped with dexmedetomidine (0.5 μg? kg -1? min-1 ) and propofol(4 μg? mL-1 ) combined with remifentanyl (4.5 ng? mL -1 ), respectively.Narcotrend scale, heart rate ( HR) and mean arterial pre-ssure(MAP) were recorded at the beginning of anesthesia (T0), before cut skin ( T1 ) , when the craniotomy ( T2 ) , waking up ( T3 ) , at every 5 min before 10 min of the beginning of waking up ( T4 and T5 ) , 10 min before the end of waking up ( T6 ) , abd the end of wakeing up ( T7 ) . Arousing time and recovery quality including the degree of cooperateing , bucking and agitation were also recorded .Results There was no statisti-cally significant difference of MAP and HR between the two groups at T 0 , T1, T2, T3 and T4(P>0.05).MAP, HR of treatment group at T5,T6 and T7 were lower than those of control group (P<0.05).There was no difference of Narcotrend index(NI) between the two groups(P>0.05).Arousing time and the degree of cooperateing of treatment group were significantly higher than that of control group ( P<0.05 ) .Bucking and agitation of treatment group were significantly lower than those of control group ( P<0.05 ) . Conclusion Dexmedetomidine used in language function surgery does not reduce the NI value , but can reduce the MAP and HR, maintain hemodynamic stability and reduce adverse reactions .
