“Hot-cold switch” in tumor microenvironment: Tesla Cell

VernacularTitle:肿瘤微环境“冷热转换”：细胞电池（Tesla Cell）
Author: LIU Yingting1 ^{1
,

2
,

3} ; HAN Weidong2 ^{1
,

2
,

3} ; JIANG Jingting1 ^{1
,

2
,

3}
Author Information

1. （
2. Tumor Biological Diagnosis and Treatment Center, the Third Affiliated Hospital of Soochow University, Jiangsu Tumor Immunotherapy Engineering and Technology Research Center, Cell Therapy Research Institute, Changzhou 213003, Jiangsu, China;
3. Department of Bio-Therapeutic, the First Medical Center, Chinese PLA General Hospital, Beijing 100036, China)
Publication Type:Journal Article
Keywords: 细胞电池；冷肿瘤；热肿瘤；肿瘤微环境；免疫治疗
From: Chinese Journal of Cancer Biotherapy 2024;31(12):1167-1177
CountryChina
Language:Chinese
Abstract: [摘要] 免疫疗法为肿瘤治疗提供了新手段。肿瘤患者自身微环境内免疫状态的“冷”与“热”是决定患者能否响应免疫治疗的关键在素。创新性地提出“细胞电池”促进肿瘤免疫微环境“冷热转换”的概念，并从“冷肿瘤”和“热肿瘤”的概念，“冷肿瘤”和“热肿瘤”之间的转换策略，以及“细胞电池”的种类和应用对目前肿瘤免疫治疗的研究现状和进展进行综述，为肿瘤免疫治疗新疗法的构建提供坚实的理论基础。
Full text:202502281022582416620241201.pdf