Research Advances of Neuropharmacological Effects and Mechanisms of Epigallocatechin Gallate
10.13748/j.cnki.issn1007-7693.20222313
- VernacularTitle:表没食子儿茶素没食子酸酯的神经系统药理学作用及机制研究进展
- Author:
YANG Xiangwei
1
;
LIAN Fuming
2
Author Information
1. Jining Medical University, Institute of Behavioral Medicine Education, Jining 272067, China;
2. Jining Medical University, Institute of Precision Medicine, Jining 272067, China
- Publication Type:Journal Article
- Keywords:
epigallocatechin gallate;
nervous system;
pharmacological effects;
mechanism
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(14):2032-2040
- CountryChina
- Language:Chinese
-
Abstract:
Epigallocatechin gallate(EGCG) is the most abundant component in green tea catechins. It has the functions of anti-oxidation stress, anti-inflammatory response and regulating cell apoptosis. EGCG is effective in preventing and treating tumors, improving metabolic diseases such as obesity and diabetes, treating cardiovascular diseases and neuroprotection. EGCG is the main component of tea polyphenols that plays a biological role. This paper searched and summarized the literatures related to the neuropharmacological effects of EGCG at home and abroad, so as to provide more theoretical basis for the clinical application of EGCG in the prevention and treatment of nerve injury, neurodegenerative diseases, cognitive impairment and so on.
