Comprehensive evaluation of powder-liquid double-chamber bag products: a systematic review
10.12206/j.issn.2097-2024.202312009
- VernacularTitle:粉-液双室袋产品的综合评价
- Author:
Fei SHU
1
;
Rui SUN
2
;
Kai SONG
3
;
Yuanlin ZHANG
4
;
Jiaming YAN
1
;
Lixin SHU
1
Author Information
1. Demonstration Center of Military Medical Logistics, School of Pharmacy, Naval Medical University, Shanghai 200433, China.
2. Demonstration Center of Military Medical Logistics, School of Pharmacy, Naval Medical University, Shanghai 200433, China;Gansu Armed Police Corps Hospital, Lanzhou 730050, China.
3. Demonstration Center of Military Medical Logistics, School of Pharmacy, Naval Medical University, Shanghai 200433, China;No.32106 Troops of the PLA, Ximeng 026000, China.
4. Demonstration Center of Military Medical Logistics, School of Pharmacy, Naval Medical University, Shanghai 200433, China;No.77570 Troops of the PLA, Changdu 854000, China.
- Publication Type:Pharmacyadministration
- Keywords:
powder-liquid double chamber bag;
comprehensive evaluation;
injection
- From:
Journal of Pharmaceutical Practice and Service
2025;43(2):92-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the advantages of powder-liquid double-chamber bag products compared with traditional powder injection. Methods The systematic review method was used to collect the literature on powder-liquid double-chamber bag, extract common evaluation indicators, evaluate the use value of powder-liquid double-chamber bag products, and conduct a comprehensive comparison with traditional powder injection products. Results A total of 23 articles were included in the literature. The effectiveness indicators used for evaluation were the stability of the liquid medicine, the accuracy of the preparation concentration, and the residual amount of the liquid medicine; the safety indicators were the incidence of insoluble particles and the incidence of punctures and scratches. The economic indicators were preparation cost, occupied volume of preparation supplies, waste weight, hospitalization cost and incidence of blood infection. The applicability indicators were preparation time, average occupation of medical staff, packaging weight and storage and transportation volume, environmental adaptability, and ease of waste disposal. Accessibility indicators are the number of manufacturers, raw material supply capacity, and patient affordability. Through the evaluation of literature evidence, it was found that the stability and concentration accuracy of the powder-liquid double-chamber bag were higher than those of the traditional powder injection, and the domestic supply had been achieved. The double-chamber bag method can reduce the infusion reaction and shorten the preparation time of the liquid medicine. Conclusion Compared with traditional powder injectabler products, powder-liquid double-chamber bags have advantages in the dimensions of effectiveness, safety, economy, suitability and innovation, and the accessibility dimension meets the requirements.
