Targeted biotherapy for chronic obstructive pulmonary disease
10.12092/j.issn.1009-2501.2024.04.003
- VernacularTitle:慢性阻塞性肺病的生物靶向治疗
- Author:
Haodong BAI
1
;
Bingxian SHA
;
Yadav Kumar AMBEDKAR
;
Xianghuai XU
;
Li YU
Author Information
1. 同济大学附属同济医院,呼吸与危重症医学科,上海 200065
- Keywords:
chronic obstructive pulmonary dis-ease;
targeted therapy;
cytokine
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(4):377-382
- CountryChina
- Language:Chinese
-
Abstract:
Chronic obstructive pulmonary dis-ease(COPD)is the most common chronic airway disease.The current status of treatment based mainly on bronchodilators and ICS is not sufficient for all of COPD patients.Various studies have at-tempted to use biologics targeting specific cyto-kines and their receptors in COPD patients to allevi-ate respiratory symptoms or reduce the risk of acute exacerbations.However,they failed to bring significant clinical benefits.More studies are need-ed to further determine the efficacy of targeted biotherapy for COPD.
