Opportunities and Challenges of Nasal Drug Delivery
10.13748/j.cnki.issn1007-7693.20232901
- VernacularTitle:经鼻给药的机遇与挑战
- Author:
LIAO Ping
1
;
CAO Meng
1
;
ZHANG Jingchen
2
;
CHEN Guiliang
1
Author Information
1. Shanghai Center for Drug Evaluation and Inspection, Shanghai 201210, China;
2. Yangtze River Center for Drug Evaluation and Inspection of National Medical Products Administration, Shanghai 201210, China
- Publication Type:Journal Article
- Keywords:
nasal preparation;
nasal drug delivery;
nose-to-brain delivery;
regulatory science
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(20):2761-2765
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:As a non-invasive drug delivery method, nasal drug delivery has many advantages, such as rapid onset, easy use, high compliance, no first pass effect, fewer adverse reactions, mucosal immunity, and provides a new convenient route to deliver drugs to the brain through nose-to-brain delivery. Nasal formulations are increasingly becoming a research and development hotspot, focusing on addressing unmet clinical needs. However, due to the special structure and physiology of the nasal cavity, there are still many challenges in the development and evaluation of nasal preparations.
