GC Fingerprint and GC-MS Composition Analysis of Volatile Oil in Dalitong Granules
10.13748/j.cnki.issn1007-7693.20221679
- VernacularTitle:达立通颗粒挥发油GC指纹图谱及GC-MS成分分析
- Author:
Hanyu ZHAO
1
;
Hong PENG
1
;
Chaoqing LIU
1
Author Information
1. College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China
- Publication Type:Journal Article
- Keywords:
Dalitong granules；volatile oil ； fingerprint ； GC-MS
- From:
Chinese Journal of Modern Applied Pharmacy
2024;41(6):797-804
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE :To establish the GC fingerprint of the volatile oil of Dalitong granules, and analyze the volatile oil components.
METHODS
The separation was performed on an Agilent HP-5(30 m×0.32 mm, 0.25 μm) quartz capillary column with programmed temperature and hydrogen flame ionization detector. A common pattern of 10 batches of samples was established and analyzed by a combination of chemometric methods. The volatile oil components were identified using GC-MS with NIST11.L standard library, and the origin of each component was inferred.
RESULTS
Thirteen common peaks were selected from the common chromatograms of 10 batches of samples, and the similarity of each component was >0.998, and the samples could be classified into three categories. A total of 56 components were identified by GC-MS, including 11 common peaks.
CONCLUSION
The GC fingerprint of Dalitong granules volatile oil was established with good instrument precision, reproducibility and stability, which can provide a reference basis for the quality control of Dalitong granules volatile oil.
