Analyzing the clinical characteristics of 56 cases of occupational pneumoconiosis complicated with interstitial lung disease
10.20001/j.issn.2095-2619.20240811
- VernacularTitle:职业性尘肺病合并间质性肺炎56例临床特点分析
- Author:
Mei BAI
1
;
Jiuhong ZHANG
;
Zhiqiang CHEN
;
Weiming XIE
Author Information
1. Department of Pneumoconiology Second Ward, Guangxi Prevention and Treatment Institute for Occupational Diseases, Nanning, Guangxi 530021, China
- Publication Type:Journal Article
- Keywords:
Pneumoconiosis;
Interstitial lung disease;
High resolution computed tomography;
Connective tissue disease
- From:
China Occupational Medicine
2024;51(4):415-418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features of occupational pneumoconiosis (hereinafter referred to as “pneumoconiosis”) complicated with interstitial lung disease (ILD). Methods A total of 56 patients with pneumoconiosis complicated with ILD were selected as the research subjects using a retrospective study method, and their clinical features were analyzed. Results The main clinical symptoms of the 56 patients were progressive dyspnea, cough, and expectoration, with detection rates of 76.8%, 75.0%, and 55.4%, respectively. The detection rates of hypoxemia and respiratory failure were 67.9% and 32.1% respectively. Among the 35 patients who underwent pulmonary function test, restrictive, mixed, and obstructive ventilatory disorders were detected in 37.1%, 22.9%, and 17.1% of cases, respectively, with a 74.3% detection rate for reduced diffusion capacity. High resolution computed tomography of the chest revealed ground-glass shadows, grid shadow, interlobular thickening, honeycomb shadows and tractive bronchiectasis, with detection rates of 57.1%, 35.7%, 35.7%, 23.2%, and 17.9%, respectively. Lesions were mostly diffusely distributed in both lungs, with a predominance in the lower lungs compared to the mid-upper lungs. Patients complicated with connective tissue disease, including systemic sclerosis, rheumatoid arthritis, systemic lupus erythematosus, polymyositis, and dermatomyositis, accounted for 33.9% (19 cases). Conclusion The clinical symptoms, pulmonary function, and arterial blood gas analysis results of patients with pneumoconiosis complicated with ILD show no specific features. However, a subset of pneumoconiosis patients with ILD also have coexisting connective tissue diseases.
