Application Potential of Lactic Acid Bacteria in Ophthalmology
10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).20241021.006
- VernacularTitle:乳酸菌在眼科的应用潜力
- Author:
Meilan WANG
1
;
Lian LIU
Author Information
1. 暨南大学附属第一医院眼科,广东广州 510630
- Keywords:
lactic acid bacteria;
direct effect;
indirect effect;
ophthalmic diseases;
therapy
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2024;45(6):953-960
- CountryChina
- Language:Chinese
-
Abstract:
Lactic acid bacteria(LAB) have biological functions such as nutrition,bacteriostasis and immune regulation,which play important roles in the fields of food,agriculture and animal husbandry,industry,medicine and so on. At present,in the clinical application research of LAB,the focus of attention is on gastrointestinal diseases,urinary tract infections,allergic rhinitis,anti-tumor,etc.,but there are few introductions to the research progress of LAB in ocular application. In addition to regulating inflammation,the mechanism of action of lactic acid bacteria in the treatment of eye diseases is also affected by different mechanisms,which can be divided into direct and indirect effects. This article reviews the application of lactic acid bacteria in ocular surface diseases,fungal keratitis,lens and retinal diseases,summarizes and summarizes lactic acid strains and their related mechanisms,compares the differences of different lactic acid strains in the treatment of ophthalmic diseases. The in vitro,in vivo and clinical evidence of lactic acid bacteria in ophthalmic research are summarized,and the use of lactic acid bacteria in the treatment has high safety. The application of ophthalmic diseases has shown significant innovation and clinical significance,broadened the application scope of lactic acid bacteria in ophthalmology,and provided new ideas for future clinical treatment.
