Isolation and identification of two nitrogen-containing aromatic glycosides from Scolopendra subspinipes mutilans
10.16438/j.0513-4870.2024-0083
- VernacularTitle:少棘巨蜈蚣中二个新含氮芳香苷的分离鉴定
- Author:
Shu-ping YANG
1
;
Bin-yuan HU
2
;
Yong-xian CHENG
1
Author Information
1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China; Institute for Inheritance-based Innovation of Chinese Medicine, Shenzhen University Medical School, Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics, Shenzhen 518060, China
2. Institute for Inheritance-based Innovation of Chinese Medicine, Shenzhen University Medical School, Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics, Shenzhen 518060, China
- Publication Type:Research Article
- Keywords:
Scolopendridae;
italic>Scolopendra subspinipes mutilans;
chemical component;
aromatic glycoside;
indole glycoside;
peptide
- From:
Acta Pharmaceutica Sinica
2024;59(8):2283-2287
- CountryChina
- Language:Chinese
-
Abstract:
Using column chromatography methods including the macroporous adsorbent resin, MCI gel CHP 20P, ODS-A-HG, Sephadex LH-20, combined with chromatographic separation methods such as TLC and reversed-phase HPLC, three glycosides (1-3) and two peptides including two new compounds were isolated from the ethanol extract of arthropod Scolopendra subspinipes mutilans. Their structures were identified as colosides A and B (1 and 2), 3,4-dihydroxyquinoline-4-O-β-D-glucopyranoside (3), aurantiamide (4), cyclo (L-phe-L-val) (5) by UV, NMR and HR-ESI-MS spectroscopic techniques.
