The evaluation value of FAI in CCTA for coronary artery stenosis severity and plaque vulnerability
10.13491/j.issn.1004-714X.2024.05.016
- VernacularTitle:CCTA的FAI对冠状动脉狭窄程度及斑块易损性的评估价值
- Author:
Chen YUAN
1
;
Qianqian CHEN
1
;
Ying MA
1
;
Zhong CHEN
1
Author Information
1. Huainan Oriental Hospital Group General Hospital Imaging Department, Huainan 232038 China.
- Publication Type:OriginalArticles
- Keywords:
Coronary CT;
Angiography;
Fat attenuation index;
Noncalcified plaque;
Plaque vulnerability;
Risk stratification
- From:
Chinese Journal of Radiological Health
2024;33(5):584-589
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of fat attenuation index (FAI) on coronary CT angiography (CCTA) in evaluating the degree of coronary artery stenosis and the diagnostic value of plaque vulnerability. Methods A total of 80 patients treated for coronary artery diseases from January 2021 to November 2023 were retrospectively included. All patients were diagnosed with non-calcified plaque (NCP) by CCTA examination. Patients were divided according to the severity of luminal stenosis (39 with mild stenosis, 24 with moderate stenosis, and 17 with severe stenosis). According to plaque vulnerability, the patients were divided into a vulnerable plaque group (27 cases) and a non-vulnerable plaque group (53 cases). A Spearman correlation analysis was used to evaluate the correlation between FAI and stenosis severity in patients with NCP, and a multivariate logistic regression analysis was used to explore the factors influencing vulnerable plaques. Results FAI was significantly lower in the severe stenosis group (−76.95 ± 7.91 HU) than in the mild stenosis group (−66.73 ± 7.69 HU) and the moderate stenosis group (−71.58 ± 8.65 HU), and FAI was significantly lower in the moderate stenosis group than in the mild stenosis group (t = 4.534, 2.190, 4.534, P < 0.05). The correlation analysis showed that FAI was negatively correlated with the severity of coronary artery stenosis (r = −0.726, P < 0.05). There were significant differences between vulnerable and non-vulnerable plaque groups in hypertension [23 (85.19%) vs. 30 (56.60%)], smoking history [8 (29.63%) vs. 4 (7.55)], and FAI (−67.64 ± 8.32 HU vs. −75.69 ± 7.88 HU) (t = 6.535, 6.841, 4.164, P < 0.05). The multivariate logistic regression analysis showed that FAI was a risk factor for vulnerable plaque (odds ratio = 1.439, P < 0.05). Conclusion FAI can be used to effectively assess the risk stratification of NCP and is of great significance in guiding the clinical management of patients.
