Clinical application effect of ECMO in lung transplantation for recipients with combined pulmonary fibrosis and emphysema
10.3969/j.issn.1674-7445.2024130
- VernacularTitle:ECMO在肺纤维化合并肺气肿受者肺移植术中的临床应用效果
- Author:
Jialong LIANG
1
;
Jintao ZHOU
;
Jingyu CHEN
;
Yuan CHEN
;
Shugao YE
Author Information
1. 214023 江苏无锡,南京医科大学无锡医学中心无锡市人民医院南京医科大学附属无锡人民医院肺移植中心
- Keywords:
Lung transplantation;
Idiopathic pulmonary fibrosis;
Pulmonary emphysema;
Extracorporeal membrane oxygenation;
Vein;
Artery;
Pulmonary artery hypertension;
Complication
- From:
Organ Transplantation
2024;15(6):935-941
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different extracorporeal membrane oxygenation(ECMO)bypass modes on the prognosis of patients with combined pulmonary fibrosis and emphysema(CPFE)during lung transplantation.Methods A retrospective analysis was conducted on 44 CPFE patients who underwent lung transplantation,and they were divided into the venous-venous ECMO(VV-ECMO)group(30 cases)and the venous-arterial ECMO(VA-ECMO)group(14 cases).The preoperative,intraoperative,postoperative and follow-up related indicators of two groups were compared.Results Compared with the VV-ECMO group,the patients in the VA-ECMO group were younger,had higher pulmonary artery pressure before surgery,fewer posterolateral incision types,longer operation times,and higher incidence of postoperative bronchopleural fistula(all P<0.05).The pulmonary artery pressure decreased after surgery in both groups,with a greater decrease in the VA-ECMO group(P<0.05).There was no statistically significant difference in postoperative survival rates between the two groups(P>0.05).Conclusions Both VA-ECMO and VV-ECMO are safe and effective in lung transplant patients with CPFE.The bypass mode has no significant impact on the short and medium-term prognosis of the patients.VA-ECMO is more suitable for patients with higher preoperative pulmonary artery pressure.
