The Association between Distal Colon Adenoma and the Metabolic Syndrome and Lifestyle Factors in Male Examinees in a University Hospital.
- Author:
Moon Chan KIM
1
;
Chang Sup KIM
;
Deuk Kee LEE
;
Tae Heum JEONG
Author Information
1. Department of Family Medicine, University of Ulsan College of Medicine, Ulsan, Korea. doc43327@uuh.ulsan.kr
- Publication Type:Original Article
- Keywords:
metabolic syndrome;
colorectal adenoma;
life style factor
- MeSH:
Adenoma;
Adult;
Alcohol Drinking;
Colon;
Colonic Neoplasms;
Cross-Sectional Studies;
Drinking;
Epidemiologic Studies;
Health Promotion;
Humans;
Incidence;
Inflammatory Bowel Diseases;
Korea;
Life Style;
Male;
Mass Screening;
Motor Activity;
Polyps;
Sigmoidoscopy;
Smoking
- From:Journal of the Korean Academy of Family Medicine
2008;29(3):195-200
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: According to previous epidemiologic studies, the metabolic syndrome, dietary and lifestyle factors were associated with colon polyps. The aim of this cross-sectional study was to assess the relationship between the risk of the colorectal adenoma incidence and the individual components of the metabolic syndrome with lifestyle factors such as drinking, cigarette smoking and physical activity. METHODS: Sigmoidoscopic examination for colon cancer screening was performed from January 2002 to December 2003 at the Health Promotion Center of Ulsan University Hospital in Ulsan, Korea. A total of 1,565 subjects underwent satisfactory sigmoidoscopy. The subjects with a history of colon cancer or polyps or inflammatory bowel disease were excluded from the study. Alcohol consumption, cigarette smoking and other confounding factors were included as covariates in the models. RESULTS: After adjusting for age, physical activity,smoking and alcohol intake, the subjects of metabolic syndrome (> or =3 vs. 0 components) combined with cigarette smoking had a positive association with colorectal adenoma incidence (OR 3.63, 95% CI 1.49~8.89). Physical activity was negatively associated the risk of the colorectal adenoma incidence (OR 0.60 95% CI 0.44~0.81). CONCLUSION: These results suggest that clustering of components of the metabolic syndrome combined with cigarette smoking significantly increased the colorectal adenoma risk, but physical activity reduced the risk of colorectal adenoma incidence in Korean adult males after multivariate adjustment.
