Platinum Resistance in Ovarian Cancer:Limitations of PFI Binary Classification and Potential Improvements

VernacularTitle:卵巢癌铂耐药:PFI"二分法"的局限性与可能的改进
Author: Xiaoyu LI ¹ ; Nan ZHANG ; Wen DI
Author Information

1. 200127 上海,上海交通大学医学院附属仁济医院妇产科,上海市妇科肿瘤重点实验室,肿瘤系统医学全国重点实验室
Keywords: Ovarian neoplasms; Platinum resistance; Platinum-free interval; Classification
From: Cancer Research on Prevention and Treatment 2024;51(10):813-819
CountryChina
Language:Chinese
Abstract: Ovarian cancer is a common gynecologic malignancy.In clinical practice,recurrent ovarian cancer is mainly classified into two categories on the basis of platinum-free interval,platinum-resistant and platinum-sensitive,corresponding to different treatment modalities and prognoses.The treatment of platinum-resistant ovarian cancer is challenging.Some scholars have pointed out limitations in the binary classification of platinum-free interval.In this article,the classification of recurrent ovarian cancer,the treatment challenges of platinum-resistant ovarian cancer,the limitations of the platinum-free interval binary classification,and new classification perspectives were reviewed to help physicians enhance their understanding on the research progress in ovarian cancer classification and develop more effective treatment strategies.