Clinical Manifestations and Epidemiological Characteristics of Influenza in Hubei
10.3969/j.issn.1006-2483.2024.05.022
- VernacularTitle:湖北地区流感病例临床特征和流行病学分析
- Author:
Rui WANG
1
;
Ruifeng XIAO
2
;
Ao LI
3
;
Qifei ZHANG
2
;
Bing LIU
1
Author Information
1. Hubei Medical College Health Management and Health Development Research Center , Shiyan , Hubei 442000 , China
2. School of Public Health and Health , Hubei Medical College , Shiyan , Hubei 442000 , China
3. Outpatient Department of Taihe Hospital , Shiyan , Hubei 442000 , China
- Publication Type:Journal Article
- Keywords:
Influenza;
Epidemic characteristics;
Clinical manifestations;
Influenza virus typing
- From:
Journal of Public Health and Preventive Medicine
2024;35(5):93-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical manifestations and epidemiological characteristics of influenza in Hubei. Methods Pharyngeal swab specimens from 16,500 patients with suspected influenza infection admitted to our hospital from January 2020 to December 2022 were selected. Viral detection and serotyping were performed by fluorescence quantitative polymerase chain reaction. Furthermore, the epidemiological and clinical data of patients were collected to analyze the clinical features and epidemiological characteristics of influenza viruses. Results A total of 16 500 clinical specimens were tested in this study, with a positive detection rate of 16.27% (2 684/16 500). The positive detection rate was 5.10% (862/16 500) for influenza A virus, 10.13% (1 672/16 500) for influenza B virus and 0.91% (150/16 500) for mixed influenza. The positive detection rate of influenza viruses was on the rise from 2020 to 2022 , reaching 18.43% in 2022. Seasonal distribution analysis denoted that the highest positive detection rates were observed in spring (18.23%) and winter (19.72%), with statistical difference (P<0.05). In terms of age distribution, patients<12 years (19.14%) had the highest positive detection rate, followed by those >60 years (17.71%), with statistical difference (P<0.05). From 2020 to 2022, the positive detection rate of influenza virus was 16.89% in males, which was higher than 15.63% in females (P<0.05). The main clinical symptoms were fever (86.89%) and cough (80.27%) for influenza A virus infections, cough (92.52%) and fever (86.06%) for influenza B virus infections, and cough (94.00%), fever (88.00%) and runny nose (86.00%) for mixed infections. Conclusion The influenza B viruses are the leading cause of influenza in Hubei from 2020 to 2022, and the infection demonstrates an increasing annual trend, with a high prevalence in winter and spring. Furthermore, children and the elderly are high-risk populations, and clinical manifestions are mainly cough and fever.
