Application of PSMA PET/CT in the diagnosis and treatment of localized or locally advanced prostate cancer
10.3969/j.issn.1009-8291.2024.08.002
- VernacularTitle:PSMA PET/CT在局限性或局部进展性前列腺癌诊疗中的应用
- Author:
Ning XU
1
;
Zhibin KE
;
Jiayin CHEN
Author Information
1. 福建医科大学附属第一医院泌尿外科,福建福州 350005;福建医科大学附属第一医院滨海院区国家区域医疗中心泌尿外科,福建福州 350212
- Keywords:
prostate cancer;
prostate-specific membrane antigen;
positron emission tomography/computed tomography;
clinically significant prostate cancer
- From:
Journal of Modern Urology
2024;29(8):667-672
- CountryChina
- Language:Chinese
-
Abstract:
Prostate-specific membrane antigen positron emission tomography/computed tomography(PSMA PET/CT)is an emerging imaging technique applied in the diagnosis and treatment of localized or locally advanced prostate cancer.It can effectively avoid unnecessary biopsies,and PSMA PET/CT-guided targeted biopsy could significantly improve the detection rate of clinically significant prostate cancer(csPCa).The technology of PSMA PET-based multi-image fusion biopsy may be the emphasis in the research of prostate cancer diagnosis in future.Compared with traditional imaging techniques,PSMA PET/CT is advantageous in detecting lymph node metastasis.It can not only be used to predict the adverse pathological features,including Gleason score,positive surgical margin,and postoperative pathological upgrading,but also to evaluate the efficacy of neoadjuvant therapy,guide radiotherapy regimen,predict biochemical recurrence and detect recurrent lesions.Currently,more large-scale prospective studies are still needed to explore the application of PSMA PET/CT for localized or locally advanced prostate cancer.
