Follow-up and observation on the efficacy of bladder neck contracture after radical prostatectomy via transurethral resection of bladder neck combined with triamcinolone acetonide injection
10.3969/j.issn.1009-8291.2024.06.004
- VernacularTitle:膀胱颈部电切联合曲安奈德注射治疗前列腺癌根治术后膀胱颈部挛缩疗效随访观察
- Author:
Xinyu ZHENG
1
;
Sheng LIU
;
Linlin ZHANG
;
Dalin HE
;
Lin YANG
Author Information
1. 西安交通大学第一附属医院泌尿外科,陕西西安 710061
- Keywords:
bladder neck contracture;
radical prostatectomy;
transurethral resection of bladder neck;
triamcinolone acetonide
- From:
Journal of Modern Urology
2024;29(6):492-496,500
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the efficacy and safety of transurethral resection of bladder neck combined with intraoperative and postoperative regular injection of triamcinolone acetonide in the treatment of bladder neck contracture(BNC)after radical prostatectomy(RP).Methods Clinical data of 19 patients with BNC after RP who underwent transurethral resection of bladder neck combined with intraoperative and postoperative regular triamcinolone acetonide treatment in our hospital during Mar.2018 and Mar.2023 were retrospectively analyzed.The changes in international prostate symptom score(IPSS),quality of life score(QoL)and complications were analyzed before operation,3 and 12 months after operation,and at the end of follow-up.Results All patients completed the follow-up,10 of whom received one treatment.Of the 9 patients with recurrence,6 received 2 treatments(including 2 cases of recurrence after surgery)and 1 received 3 treatments.After a mean follow-up of 3 years,the success rate of one treatment was 52.6％(10/19),and the cumulative success rate was 73.7％(14/19).The IPSS and QoL at each follow-up time point were significantly improved compared with those before surgery(P＜0.05).Postoperative complications included epididymitis in 2 cases(10.5％),transient hematuria in 2 cases(10.5％),and urinary incontinence in 11 cases(57.9％),including 6 new cases of urinary incontinence,and 5 cases whose urinary incontinence lasted to the end of follow-up.Conclusion Bladder neck resection combined with intraoperative and postoperative regular triamcinolone acetonide injection has a successful rate of 73.7％in the treatment of BNC after RP.However,some patients require multiple operations,and the incidence of postoperative urinary incontinence is high and the recovery is slow.
