Evolution of resuscitation fluid for hemorrhagic shock——low titer group O whole blood is becoming preferred e-mergent universal bridging resuscitation fluid

VernacularTitle:失血性休克复苏液体的演进
Author: Hongjie WANG ¹ ; Yongjian GUO
Author Information

1. 北京市红十字血液中心,北京 100083;国家卫生健康标准委员会血液标准专业委员会
Keywords: low titer group O whole blood(LTOWB); resuscitation; hemorrhagic shock
From: Chinese Journal of Blood Transfusion 2024;37(8):953-964
CountryChina
Language:Chinese
Abstract: Timely and effective blood resuscitation is very important for patients with severe blood loss.The resuscitation fluids for hemorrhagic shock have evolved from whole blood to crystalloid/colloid solutions,crystalloid combined with red blood cells,to balanced blood components.In the past 20 years,it is a growing trend that low titer antibody group O whole blood(LTOWB)is used as the preferred universal bridging resuscitation fluid for emergent blood resuscitation.Herein we provide a review of the history and current status of whole blood for patients with severe bleeding and make a suggestion to launch a national implementation research program of LTOWB in China.