Clinico-radiological outcome of Arthroscopic Anterior Cruciate Ligament Reconstruction with Augmentation of Dehydrated Human Amnion Chorion Allograft Membrane using Peroneus Longus Autograft
https://doi.org/10.5704/MOJ.2403.005
- Author:
Tonape PB
1
;
Kishore JVS
2
;
Kopparthi RM
3
;
Tonape T
4
;
Bhamare DS
2
;
Desireddy S
5
Author Information
1. Department of Orthopedics, Sterling Multispeciality Hospital, Pune, India
2. Department of Orthopedics, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, India
3. Department of Radiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, India
4. Department of General Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, India
5. Department of Research, Pune, India
- Publication Type:Journal Article
- Keywords:
anterior cruciate ligament reconstruction, dehydrated human amnion chorion membrane, allograft, signal-to-noise ratio, tegnor lysholm score
- From:Malaysian Orthopaedic Journal
2024;18(No.1):33-41
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: For many sportsmen, anterior cruciate
ligament (ACL) tears are unfortunate but common injuries.
Several growth factors, cytokine, chemokine, and protease
inhibitors functions in stimulation of paracrine reactions in
fibroblast, endothelial, and stem cells thereby promoting the
tissue restorative processes. Augmented with dehydrated
Human Amnion Chorion Membrane (dHACM) allograft
reinforces the reconstructed ligament and aids in effective
restoration.
Materials and methods: In this case control study 15
patients undertaking ACL reconstruction with tripled
peroneus augmented dHACM (G1) were prospectively
monitored up for a period of 8 months along with 15 control
patients (G2) without dHACM augmentation. Clinical and
radiological outcomes were analysed and assessed about
effect of augmenting the peroneus longus graft using
dHACM. Clinical analysis included pre-operative two, four,
six, and eight months post-operative Tegnor-Lysholm score,
and radiological analysis included the 6th month postoperative MRI signal-to-noise ratio (SNR) measurements by
mean signal-value at femoral insertion, midsubstance and
tibial insertion of ACL graft.
Results: Clinically, as a mean Lysholm score of all patients,
they were revealed to be consecutively high in G1 than in
Group 2 at four, six, and eight months. The signal-to-noise
ratio from the MRI results showed majority having good
healing in G1 group.
Conclusions: Based on 6-month MRI, an effective
ligamentization (SNR<75) was noticed in 53.33% of patients
in the dHACM allograft enhanced group on comparison with
33% in the controls. The overall results show that the
augmentation of dHACM allograft to ACL reconstruction
yields in good patient outcomes at post-operative follow-up.
- Full text:202408071210158978016.2024my1349.pdf
