Research progress on the effects of proanthochanidins in reshaping microbiota and suppressing inflammation.
10.3760/cma.j.cn112150-20230518-00392
- VernacularTitle:原花青素重塑菌群及抗炎作用的研究进展
- Author:
Wei Wei LI
1
;
Yi Qing LIU
1
;
Xing LIU
1
;
Wei QU
1
Author Information
1. Department of Clinical Laboratory, Guiyang Maternal and Child Health Care Hospital,Guiyang 550003,China.
- Publication Type:Journal Article
- MeSH:
Humans;
Female;
Microbiota;
Inflammation;
Proanthocyanidins/therapeutic use*;
Anti-Bacterial Agents/therapeutic use*
- From:
Chinese Journal of Preventive Medicine
2023;57(10):1711-1718
- CountryChina
- Language:Chinese
-
Abstract:
Proanthocyanidins (PCs) are a class of polyphenols that are composed of flavanate monomers and their polymers, which have antibacterial and anti-inflammatory properties with very few side effects. This article reviews the mechanism by which PCs differentially regulate microbiota, reshape microflora diversity and play a role in suppressing inflammation, providing a reference for the basic research of PCs in improving female vaginal health, and is expected to provide a new idea and breakthrough for the combined use of PCs with other antibacterial drugs in the treatment of vaginitis.