Research progress on differential diagnosis of thalassemia trait and iron deficiency anemia by blood erythrocyte parameters
10.3760/cma.j.cn112150-20230601-00427
- VernacularTitle:利用全血红细胞指数鉴别地中海贫血与缺铁性贫血的研究进展
- Author:
Lixia CUI
1
;
Ling JI
Author Information
1. 汕头大学医学院临床检验诊断学系，汕头 515100
- Keywords:
Thalassemia trait;
Iron deficiency anemia;
Erythrocyte parameters;
Differential diagnosis
- From:
Chinese Journal of Preventive Medicine
2024;58(1):122-127
- CountryChina
- Language:Chinese
-
Abstract:
Thalassemia trait is an autosomal recessive genetic disease, which is a hemolytic anemia caused by disturbance of erythrocyte hemoglobin production caused by gene mutation or deletion. Iron deficiency anemia is caused by a lack of iron in the body due to an imbalance between the demand and supply of iron. The laboratory manifestations of both are microcytic hypochromic anemia, but the treatment schemes are completely different, and it is difficult to distinguish them from the results of blood count. Erythrocyte parameters can be used to establish a formula or model to differentiate them, which can achieve the purpose of early screening, early diagnosis and early treatment,preventing the occurrence of severe anemia and providing a scientific basis for the thalassemia and iron deficiency anemia prevention. This article will review the research progress of using erythrocyte parameters to distinguish thalassemia trait with iron deficiency anemia.
