Research progress of chronic obstructive pulmonary disease in young people and pre-COPD.
10.3760/cma.j.cn112150-20220929-00939
- VernacularTitle:早发型慢性阻塞性肺疾病和慢性阻塞性肺疾病前期的研究进展
- Author:
Yao Pin HAN
1
;
Bin Feng HE
1
;
Jing ZHANG
1
Author Information
1. Department of Pulmonary and Critical Care Medicine, Zhongshan hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Aged;
Adolescent;
Pulmonary Disease, Chronic Obstructive;
Lung;
Cohort Studies;
Research Design
- From:
Chinese Journal of Preventive Medicine
2023;57(8):1164-1170
- CountryChina
- Language:Chinese
-
Abstract:
Conventional wisdom holds that the onset of chronic obstructive pulmonary disease (COPD) is usually in older people. However, with extended follow-up in large cohort studies, the trajectory of lung function development has been gradually delineated, indicating that the decline of lung function may originate early in life. In addition, a large number of studies have shown that people with chronic respiratory symptoms, pulmonary imaging changes and abnormal lung physiology, but not in line with pulmonary function diagnosis of COPD, tend to develop COPD in the future and may have a worse prognosis, suggesting the necessity of early intervention. The GOLD 2022 report proposes a series of terms related to COPD, including COPD in young people and pre-COPD, opening up new opportunities for the prevention, early diagnosis and treatment of COPD. These concepts also guide the study design of the biological mechanism of COPD and the trajectory of disease progression. This article reviews the research progress of COPD in young people and pre-COPD to attract more attention in clinical practice.
