The Use of Pancreatic Exocrine Insufficiency-Questionnaire (PEI-Q)
10.15279/kpba.2024.29.2.41
- Author:
Tae In KIM
1
;
Sung Yong HAN
;
Jonghyun LEE
;
Dong Uk KIM
;
Min Kyu JUNG
Author Information
1. Division of Gastroenterology, Pusan National University Hospital, Busan, Korea
- Publication Type:Review Article
- From:Korean Journal of Pancreas and Biliary Tract
2024;29(2):41-45
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chronic pancreatitis is a non-reversible, progressive inflammatory disease of the pancreas that is caused by repeated inflammation. It is characterized by morphological changes in the parenchyma and main pancreatic duct as pancreatic tissue is damaged and fibrosis progresses. These changes can lead to exocrine and endocrine dysfunction in patients with chronic pancreatitis, with major complications including pain, endocrine or exocrine insufficiency, and increased risk of pancreatic cancer. Of these, pancreatic exocrine insufficiency (PEI) is a state of malabsorption in which more than 15 g of fat is excreted per day. It can be diagnosed and assessed using several methods, but these methods are currently difficult to use in Korea and have low compliance, making them low utility. Recently, the PEI-questionnaire (PEI-Q) was developed to diagnose and assess patients’ exocrine insufficiency. It has been validated in foreign countries and has the potential to be used as a tool for diagnosing exocrine insufficiency with simple questions. This paper will review the diagnostic methods for existing exocrine insufficiency and the usefulness and utilization of the PEI-Q.
