Evaluation of the Appropriateness of Platelet Transfusions at Two Tertiary Hospitals
	    		
		   		
		   			
		   		
	    	
    	 
    	10.17945/kjbt.2024.35.1.3 3
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yu Been OH
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ha Jin LIM
			        		
			        		;
		        		
		        		
		        		
			        		Yong Jun KWON
			        		
			        		;
		        		
		        		
		        		
			        		Yong Jun CHOI
			        		
			        		;
		        		
		        		
		        		
			        		Joo-Heon PARK
			        		
			        		;
		        		
		        		
		        		
			        		Hyun-Jung CHOI
			        		
			        		;
		        		
		        		
		        		
			        		Hyun-Woo CHOI
			        		
			        		;
		        		
		        		
		        		
			        		Seung-Jung KEE
			        		
			        		;
		        		
		        		
		        		
			        		Eun-Hee NAH
			        		
			        		;
		        		
		        		
		        		
			        		Myung-Geun SHIN
			        		
			        		;
		        		
		        		
		        		
			        		Jong Hee SHIN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Laboratory Medicine, Chonnam National University Hospital, Gwangju, Korea
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
            
            
            	- From:Korean Journal of Blood Transfusion
	            		
	            		 2024;35(1):33-43
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	 Background:Appropriate platelet transfusion is essential for patient blood management and allocating limited healthcare resources. Therefore, this study evaluated the appropriateness of platelet transfusion in two tertiary hospitals. 
				        	
				        
				        	Methods:At Chonnam National University Hospital (Hospital A) and Chonnam National University Hwasun Hospital (Hospital B), 1,470 platelet transfusions (299 and 1,171 cases at Hospitals A and B, respectively) during a single month were reviewed retrospectively using the Korean Transfusion Guidelines (5th edition). 
				        	
				        
				        	Results:The most common indications were therapeutic transfusion to ensure hemostasis (54.8%) at Hospital A and to prevent spontaneous bleeding in patients with hematologic/oncologic diseases (65.8%) at Hospital B. Overall, 87.3% and 76.3% of transfusions were appropriate at Hospitals A and B, respectively. According to the different transfusion indications, the therapeutic transfusions were appropriate in more than 80% of cases in both hospitals.The appropriateness of prophylactic transfusions against spontaneous bleeding was 80.7% and 69.3%, respectively, and those before surgery or invasive procedures were 72.0% and 66.2%, respectively. Of the 38 and 278 inappropriate transfusions in Hospitals A and B, respectively (as determined by pre-transfusion platelet counts), most cases had platelet counts between 50 and 100×109 /L in Hospital A (23 cases) and between 20 and 50×109 /L in Hospital B (198 cases). 
				        	
				        
				        	Conclusion:The two hospitals differed in terms of transfusion indications, appropriateness, and cases of inappropriateness. The indications and appropriateness of platelet transfusion should be reviewed in real practice on a hospital-by-hospital basis to improve transfusion management.