Symptoms and comorbidities in patients with cerebral infarction accompanied with folic acid reduction
10.19845/j.cnki.zfysjjbzz.2021.0181
- VernacularTitle: 合并叶酸降低的脑梗死患者症状和伴随疾病特征分析
- Author:
Aiyong YU
1
;
Jianjun SUN
1
;
Liu YANG
1
Author Information
1. Department of Neurology,Song Jiang Hospital Affiliated to Shanghai Jiao Tong University of Medicine,Preparatory Stage,Shanghai 201699,China
- Publication Type:Journal Article
- Keywords:
Folate;
Dementia;
Cerebral infarction
- From:
Journal of Apoplexy and Nervous Diseases
2021;38(8):681-684
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the symptoms and comorbidities of patients with cerebral infarction combined with decreased serum folic acid levels.Methods Patients were classified as folic acid-reduced cerebral infarction group（n=372） and folate normal cerebral infarction group（n=218）.The symptoms and concomitant disease state characteristics of the two groups were compared.Results Compared with the normal folic acid group,patients in the folic acid-reduced group developed bilateral lower extremity fatigue and decreased memory,walking instability（P=0.001、0.011、0.001,respectively）.Through binary unconditional Logistic regression analysis,it was found that a history of symptomatic cerebral infarction,dementia,diabetes,atrial premature beat,left ventricular hypertrophy,homocysteine are all related to the reduction of folic acid（P=0.000、0.011、0.002、0.002、0.032、0.006 respectively）.Conclusion Cerebral infarction patients with reduced folic acid manifested as bilateral lower extremity weakness,walking instability,and decreased memory.Most patients had multiple history of cerebral infarction,dementia,hyperhomocysteinemia,and heart damage.
- Full text:2024072919282216928Symptoms and comorbidities in patients with cerebral infarction accompanied with folic acid reduction.pdf
