The relationship and influencing factors between serum Cys-C,UA,CD4+and CD8+ and intracranial artery stenosis in cerebral infarction and analysis of influencing factors
10.19845/j.cnki.zfysjjbzz.2022.0076
- VernacularTitle:血清Cys-C、UA、CD4+、CD8+与脑梗死颅内动脉狭窄的关系及影响因素分析
- Author:
Dajun LI
1
;
Ping JIN
1
Author Information
1. Affiliated Hospital of West Anhui Health Vocational College,Liu an 237008,China
- Publication Type:Journal Article
- Keywords:
Cerebral infarction ； Intracranial artery stenosis ； Cystatin C ； Uric acid； T cell subsets ； Influencing factor
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(4):297-301
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between serum cystatin C (Cys-C),uric acid (UA)，CD4+T cells and CD8+T cells with intracranial artery stenosis and cerebral infarction and analyze their influencing factors.Methods The clinical data of 124 patients with cerebral infarction who were hospitalized in our hospital from June 2020 to September 2021 were collected.All patients were given Brain MRA or /and CTA and routine biochemical examinations.According to the degree of proximal stenosis of intracranial large vessels，patients were divided into no stenosis group (36cases),mild stenosis group (43 cases),and moderate to severe stenosis group (45 cases).The clinical data of the three groups of patients and the differences in serum Cys-C,UA,and T cell subsets were compared.The factors affecting intracranial artery stenosis in cerebral infarction were analyzed by multivariate Logistic regression.The ROC curve was used to evaluate the value of serum CysC,UA and T cell subsets in patients with the cerebral infarction intracranial artery stenosis narrow.Results The serum levels of Cys-C,UA,CD4+T cells were lower in no stenosis group than those in mild stenosis group and those in medium-severe stenosis group,and positively correlated with cerebral infarction intracranial artery stenosis.The serum levels of CD8+T cells were higher in no stenosis group than those in mild stenosis group and those in medium-severe stenosis group,and were negatively correlated with cerebral infarction intracranial artery stenosis.Conclusion The increase of serum Cys- C,UA,CD4+ T cells and the decrease of CD8+T cells are risk factors for intracranial artery stenosis in cerebral infarction.As the degree of intracranial artery stenosis worsens,Cys-C,UA,CD4+T cells increase,and CD8+T cells decrease.
- Full text:2024072520465325523The relationship and influencing factors between serum Cys-C,UA,CD4+and CD8+ and intracranial artery stenosis in cerebral infarction and analysis of influencing factors.pdf
