Clinical characteristic and etiological analysis of acute middle cerebellar peduncles lesions
- VernacularTitle:急性桥臂病变的临床特征及病因学分析
- Author:
Juan WANG
1
;
Meijiao ZHANG
1
;
Jianfeng WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Middle cerebellar Peduncles ； Clinical characteristic ； Etiological
- From: Journal of Apoplexy and Nervous Diseases 2022;39(7):637-643
- CountryChina
- Language:Chinese
- Abstract: To analyze the clinical characteristic and diagnosis of patients with acute middle cerebellar peduncles lesions，explore etiology and related mechanism，and improve the cognition of related diseases involving the middle cerebellar peduncles.Methods82 inpatients with middle cerebellar peduncles high signal on DWI in our hospital were analyzed retrospectively from January 2010 to December 2020.The clinical characteristic and diagnosis were summarized，and the etiology and related mechanism were further discussed.Results①All the patients had acute onset，with dizziness/vertigo as the main symptom and ataxia as the main physical sign，accompanied by limb weakness or numbness，arrhythmia，walking instability，etc.②68 cases（82.9%）had unilateral middle cerebellar peduncles lesions，14 cases（17.1%）had bilateral middle cerebellar peduncles lesions，③72 cases（87.8%）were diagnosed with acute cerebral infarction；7 cases（8.5%）were diagnosed with Wallerian degeneration；1 case（1.2%）had high probability of diagnosis of immune-related demyelinating disease of central nervous system；1 case（1.2%）had high probability of diagnosis of primary lymphoma of the central nervous system and 1 case（1.2%）was diagnosed MOG antibody disease. ④Among 72 patients with acute cerebral infarction，20 cases（27.8%）were isolated unilateral middle cerebellar peduncles infarction，11 cases（55.0%）were aortic large large-artery atherosclerosis，5 cases（25.0%）were smallartery occlusion，and 4 cases（20.0%）were undetermined etiology. 45 patients（62.5%）had unilateral middle cerebellar peduncles accompanied by infarctions in other sites，of which 33 cases（73.3%）were largeartery atherosclerosis，4 cases（8.9%）were Cardioembolism，and 9 cases（20.0%）were undetermined etiology. The etiology of 2 cases of isolated bilateral middle cerebellar peduncles infarction and 5 cases of bilateral middle cerebellar peduncles combined by infarction in other sites is large-artery atherosclerosis. Conclusion（1）The most common clinical symptom of acute middle cerebellar peduncles lesions is dizziness/vertigo，and the most common etiology is cerebral infarction.（2）Middle cerebellar peduncles infarction is often combined by infarction in other parts，isolated middle cerebellar peduncles infarction and bilateral middle cerebellar peduncles infarction are relatively rare，and the main etiological is large-artery atherosclerosis.（3）Involvement of the middle cerebellar peduncles may also occur with Wallerian degeneration，immune-related demyelinating disease of central nervous system，MOG antibody disease，and central nervous lymphoma may also be involved.
- Full text:2024072323542696788Clinical characteristic and etiological analysis of acute middle cerebellar peduncles lesions.pdf
