Prevalence and outcomes of COVID-19 pneumonia and bacterial pneumonia co-infection among COVID-19 patients admitted in Cebu Velez General Hospital: A cross-sectional study
- Author:
Joana Marie E. Gantuangco
1
;
Shayne Julieane L. Morales
2
;
Lalaine M. Mayol
1
;
Concordio John T. Toring
1
;
Noridja C. Yusop
1
;
Bayani Pocholo T. Maglinte
1
;
Jeremyjones F. Robles
3
Author Information
- Publication Type:Journal Article
- Keywords: Bacterial pneumonia co-infection; Empiric antibiotic
- MeSH: COVID-19; Pneumonia
- From: Philippine Journal of Internal Medicine 2024;62(2):83-86
- CountryPhilippines
- Language:English
-
Abstract:
Background:Studies on previous viral pandemics showed poorer outcomes of patients with concomitant bacterial
infection. During the early period of COVID-19 pandemic, empiric antibiotic therapy is commonly given among COVID-19
patients despite lack of strong recommendations for its use.
Objectives:We determined the prevalence of bacterial co-infection and of empiric use of antibiotics among COVID-19 admissions. We also determined association between COVID-19 severity, ICU admissions, length of hospital stay, and mortality outcomes of those with and without bacterial co-infection.
Methods:A total of 159 patients hospitalized with COVID-19 from April 2020 to April 2021 were analyzed in this crosssectional chart review study. Data on empiric antibiotic administration and cultures taken within 3 days of admission were collected. Chi-square, Fischer-Exact, and T-tests were used to analyze the data.
Results:Empiric antibiotics were given in 94.97% of COVID-19 admissions with azithromycin as the most common agent. The prevalence of bacterial co-infection among COVID-19 admitted patients was 10%. There were higher ICU admissions and longer hospital stay among those with bacterial co-infection although it did not reach statistical significance. No mortality was seen among patients with bacterial co-infection.
Conclusion:There was a high use of empiric antibiotic treatment in hospitalized COVID-19 patients despite the low prevalence of bacterial co-infection among these cases. This warrants development of strategies for antimicrobial stewardship programs especially during the COVID-19 pandemic. - Full text:20240627115454567932 2022-210 OK.pdf
