Recent advance in effect and dietary intervention of PM2.5 on Parkinson's disease
10.3760/cma.j.cn115354-20221028-00753
- VernacularTitle:PM2.5对帕金森病的影响及饮食干预研究进展
- Author:
Yu TIAN
1
;
Xiujun WANG
Author Information
1. 浙江大学医学院基础医学系，杭州 310058
- Keywords:
Particulate matter 2.5;
Parkinson's disease;
Oxidative stress;
Inflammatory response
- From:
Chinese Journal of Neuromedicine
2023;22(5):536-540
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease (PD) is the second largest neurodegeneration disease in the world, characterized by tremors, rigidity and bradykinesia. Fine particulate matter (PM2.5) is a kind of airborne particulate matters whose diameter≤2.5 μm. Epidemiological studies have shown that PM2.5 is associated with PD, and both short-term and long-term exposures to PM2.5 can increase PD risk. However, few relevant studies and still unclear mechanism are noted; therefore, this article reviews the epidemiological studies, mechanism and dietary intervention strategies of PM2.5 and PD.
