Application of digital 3D reconstruction model in transsphenoidal microsurgery for pituitary tumors
10.3760/cma.j.cn115354-20220420-00253
- VernacularTitle:数字化三维重建模型在经鼻蝶垂体瘤显微切除术中的应用
- Author:
Amuti Wulajiang· MAI
1
;
·Tuerxun MAIMAITIAILI
;
·Mansuer ALIMU
;
Guiqin ZHAO
;
Zhengqing LIU
Author Information
1. 喀什地区第一人民医院神经外科，喀什 844000
- Keywords:
Pituitary adenoma;
Digital three-dimensional reconstruction;
Transsphenoidal endoscopic surgery;
Microsurgery
- From:
Chinese Journal of Neuromedicine
2022;21(7):691-696
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of digital three-dimensional reconstruction model of pituitary adenoma in transsphenoidal endoscopic pituitary adenoma resection.Methods:Fifty-eight patients with endoscopic pituitary, admitted to our hospital from July 2020 to March 2022, were chosen. All patients accepted transsphenoidal surgery under microscope and were randomly assigned to a control group (without digital 3D reconstruction technology before surgery) and a model group (with digital 3D reconstruction technology before surgery). The tumor size, preoperative and postoperative hormone levels, surgical duration, intraoperative blood loss, extent of surgical resection, and complications 3 months after follow up were compared.Results:There was no significant difference in age, gender, tumor types, tumor sizes and Knosp grading between the two groups ( P>0.05), indicating comparability. The resection degree of pituitary tumor in model group was better than that that in control group; the proportion of patients with total and subtotal resection in the model group was significantly higher than that in the control group (24/29 vs. 16/29, P=0.045). Intraoperative blood loss, surgical duration and average hospital stay in the model group were significantly decreased as compared those in the control group ( P<0.05); the duration of tumor resection in the model group ([46.93±10.77] min) was significantly shorter than that in the control group ([56.00±12.47] min, P<0.05). The levels of prolactin and human growth hormone in the model group 1 and 7 d after surgery were decreased as compared with those in the control group, without significant differences ( P>0.05). Three months after follow-up, the incidences of diabetes insipidus, hyponatremia and hypopituitarism in model group were significantly lower than those in control group ( P<0.05). The satisfaction rate in the model group was significantly higher than that in the control group ( P<0.05). Conclusion:The construction of digital three-dimensional reconstruction model of pituitary adenoma is helpful in understanding the adjacent relationship between tumors, nerves, and blood vessels before surgery, develop personalized surgical plan and improve surgical efficiency.
