Mechanism and clinical research progress of pyroptosis in spinal cord injury
10.3760/cma.j.cn115354-20210924-00624
- VernacularTitle:焦亡在脊髓损伤中的作用机制及临床研究进展
- Author:
Yi ZHAO
1
;
Yanjie JIA
Author Information
1. 郑州大学第一附属医院神经内科，郑州 450052
- Keywords:
Spinal cord injury;
Pyroptosis;
Inflammasome
- From:
Chinese Journal of Neuromedicine
2022;21(4):409-413
- CountryChina
- Language:Chinese
-
Abstract:
A large number of studies have shown that the expressions of pyroptosis-related molecules are up-regulated in spinal cord injury (SCI) animal models. Neuroinflammation alleviation by inhibiting pyroptosis will be a new target for treating SCI. This article reviews the mechanism and clinical application of pyroptosis in SCI, in order to provide references for SCI treatment.
