Recent advance in role of endogenous small molecule substance metabolism in blood samples in depression

VernacularTitle:血液内源性小分子物质代谢在抑郁症中的研究进展
Author: Jing DING ¹ ; Yan ZHANG ; Caiping ZHAO ; Suo ZHANG
Author Information

1. 西安市精神卫生中心药学实验室，西安　710100
Keywords: Depression; Blood; Endogenous small molecule; Biomarker; Metabonomics
From: Chinese Journal of Neuromedicine 2022;21(3):299-304
CountryChina
Language:Chinese
Abstract: Depression is a kind of severe psychiatric disorders whose risk prediction, classification, diagnosis, and prognosis lack sufficient objective basis. Metabolomics is an emerging discipline that is developed recently after genomics and proteomics, which provides new ways for examining the etiology, diagnosis, mechanism, and prognosis, and screening potential biomarkers in depression. Blood samples are easy to obtain and have less trauma, which contains almost all small molecular products in the body. This paper reviews the recent researches of blood endogenous small molecule substance metabolism in depression, in order to provide more theoretical basis and exploration direction for further study of metabolomics of depression.