Recent advance in relations of plasticity related gene proteins with nervous system functions and diseases
10.3760/cma.j.cn115354-20200102-00002
- VernacularTitle:可塑性相关基因蛋白与神经系统功能及疾病的关系研究
- Author:
Xingfeng LIU
1
;
Zhi XIAO
Author Information
1. 遵义医科大学，贵州省麻醉与器官保护基础研究重点实验室/贵州省普通高等学校脑科学特色重点实验室，遵义 563000
- Keywords:
Plasticity-related gene;
Synaptic plasticity;
Nervous function
- From:
Chinese Journal of Neuromedicine
2020;19(4):417-421
- CountryChina
- Language:Chinese
-
Abstract:
Plasticity related gene(PRG) is a subclass of the lipid phosphate phosphatase super family, which is predominantly expressed in the central nervous system in a subtype specific pattern. PRG may be involved in mechanism of nervous system functions and pathogenesis of neuropsychiatric diseases via neuron-specific transcriptional regulation, protein-protein interaction and intracellular signaling pathway regulation. Therefore, this paper reviews the progresses of PRG in recent years and prospects the future research direction.
